Contraindicated. Coadministration of doravirine with a solid CYP3A inducer could minimize doravirine plasma concentrations and/or effects. Likely for lack of virologic response and doable resistance to doravirine.Keep an eye on Intently (1)pentobarbital will reduce the extent or result of tofacitinib by influencing hepatic/intestinal enzyme CYP3A4